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The episomal replication of the prototype vector pEPI-1 depends on a transcription unit starting from the constitutively expressed Cytomegalovirus immediate early promoter (CMV-IEP) and directed into a 2000 bp long matrix attachment region…
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Even though our results suggest that DC activation plays an important role in the rescue of exhausted CD8 T cells, it is important to take into account that the presence of conventional CD4 T cells was required for the rescue of exhausted…
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